Immune Cell-Epithelial/Mesenchymal Interaction Contributing to Allergic Airway Inflammation Associated Pathology

Immune Cell-Epithelial/Mesenchymal Interaction Contributing to Allergic Airway Inflammation Associated Pathology

The primary function of the lung is efficient gas exchange between alveolar air and alveolar capillary blood. At the same time, the lung protects the host from continuous invasion of harmful viruses and bacteria by developing unique epithelial barrier systems. Thus, the lung has a complex architectu...

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Bibliographic Details
Main Authors: Kiyoshi Hirahara, Kenta Shinoda, Yuki Morimoto, Masahiro Kiuchi, Ami Aoki, Jin Kumagai, Kota Kokubo, Toshinori Nakayama
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
iBALT
pathogenic Th2 (Tpath2) cells
fibrosis
Amphiregulin (AREG)
osteopontin (OPN, Spp1)
inflammatory eosinophils
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00570/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00570/full

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