Alcaligenes is commensal bacteria habituating in the gut-associated lymphoid tissue for the regulation of the intestinal IgA responses

Secretory-immunoglobulin A (S-IgA) plays an important role in immunological defense in the intestine. It has been known for a long time that microbial stimulation is required for the development and maintenance of intestinal IgA production. Recent advances in genomic technology have made it possible...

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Bibliographic Details
Main Authors: Jun eKunisawa, Hiroshi eKiyono
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Immunology
Subjects:
IgA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00065/full