Lonidamine Causes Inhibition of Angiogenesis-Related Endothelial Cell Functions

Lonidamine Causes Inhibition of Angiogenesis-Related Endothelial Cell Functions

The aim of this study was to assess whether lonidamine (LND) interferes with some steps in angiogenesis progression. We report here, for the first time, that LND inhibited angiogenic-related endothelial cell functions in a dose-dependent manner (1-50 μg/ml). In particular, LND decreased proliferati...

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Bibliographic Details
Main Authors: Donatella Del Bufalo, Daniela Trisciuoglio, Marco Scarsella, Giulia D'Amati, Antonio Candiloro, Angela Iervolino, Carlo Leonetti, Gabriella Zupi
Format: Article
Language:English
Published: Elsevier 2004-09-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Angiogenesis
lonidamine
endothelial cells
metalloproteinases
cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558604800289

Internet

http://www.sciencedirect.com/science/article/pii/S1476558604800289

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