Plant-Derived Purification, Chemical Synthesis, and In Vitro/In Vivo Evaluation of a Resveratrol Dimer, Viniferin, as an HCV Replication Inhibitor

Plant-Derived Purification, Chemical Synthesis, and In Vitro/In Vivo Evaluation of a Resveratrol Dimer, Viniferin, as an HCV Replication Inhibitor

Oligostilbenoid compounds, a group of resveratrol multimers, display several anti-microbial activities through the neutralization of cytotoxic oxidants, and by inhibiting essential host and viral enzymes. In our previous study, we identified a series of oligostilbenoid compounds as potent hepatitis...

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Bibliographic Details
Main Authors: Sungjin Lee, Karabasappa Mailar, Mi Il Kim, Minkyung Park, Jiseon Kim, Dal-Hee Min, Tae-Hwe Heo, Soo Kyung Bae, Wonjun Choi, Choongho Lee
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Viruses
Subjects:
hepatitis C virus (HCV)
viniferin
antiviral activity
NS3 helicase inhibitor
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4915/11/10/890

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https://www.mdpi.com/1999-4915/11/10/890

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