The preclinical evaluation of immunocontraceptive vaccines based on canine zona pellucida 3 (cZP3) in a mouse model

Abstract Background Stray dogs are the reservoirs and carriers of rabies and are definitive hosts of echinococcosis. To control the overpopulation of stray dogs, zona pellucida 3 (ZP3), a primary receptor for sperm, is a potential antigen for developing contraceptive vaccines. To enhance the immune...

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Bibliographic Details
Main Authors: Ying Wang, Yijie Li, Beibei Zhang, Fuchun Zhang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Reproductive Biology and Endocrinology
Subjects:
Dog
Online Access:http://link.springer.com/article/10.1186/s12958-018-0362-x