Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric

<p>Abstract</p> <p>Background</p> <p>Glaucoma is a chronic neurodegenerative disease of the retina, characterized by the degeneration of axons in the optic nerve and retinal ganglion cell apoptosis. DBA/2J inbred mice develop chronic hereditary glaucoma and are an impor...

Full description

Bibliographic Details
Main Authors: Janssen Katherine T, Dietz Joel A, Li Yan, Schlamp Cassandra L, Nickells Robert W
Format: Article
Language:English
Published: BMC 2006-10-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/7/66