An agent-based model of dengue virus transmission shows how uncertainty about breakthrough infections influences vaccination impact projections.

Prophylactic vaccination is a powerful tool for reducing the burden of infectious diseases, due to a combination of direct protection of vaccinees and indirect protection of others via herd immunity. Computational models play an important role in devising strategies for vaccination by making project...

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Bibliographic Details
Main Authors: T Alex Perkins, Robert C Reiner, Guido España, Quirine A Ten Bosch, Amit Verma, Kelly A Liebman, Valerie A Paz-Soldan, John P Elder, Amy C Morrison, Steven T Stoddard, Uriel Kitron, Gonzalo M Vazquez-Prokopec, Thomas W Scott, David L Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006710