Diffusion Tensor Imaging of the Sciatic Nerve as a Surrogate Marker for Nerve Functionality of the Upper and Lower Limb in Patients With Diabetes and Prediabetes

BackgroundNerve damage in diabetic neuropathy (DN) is assumed to begin in the distal legs with a subsequent progression to hands and arms at later stages. In contrast, recent studies have found that lower limb nerve lesions in DN predominate at the proximal sciatic nerve and that, in the upper limb,...

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Main Authors: Johann M. E. Jende, Zoltan Kender, Christoph Mooshage, Jan B. Groener, Lucia Alvarez-Ramos, Jennifer Kollmer, Alexander Juerchott, Artur Hahn, Sabine Heiland, Peter Nawroth, Martin Bendszus, Stefan Kopf, Felix T. Kurz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.642589/full