Small Extracellular Vesicles from Head and Neck Squamous Cell Carcinoma Cells Carry a Proteomic Signature for Tumor Hypoxia

Small Extracellular Vesicles from Head and Neck Squamous Cell Carcinoma Cells Carry a Proteomic Signature for Tumor Hypoxia

Tissue hypoxia is commonly observed in head and neck squamous cell carcinomas (HNSCCs), resulting in molecular and functional alterations of the tumor cells. The aim of this study was to characterize tumor-derived small extracellular vesicles (sEVs) released under hypoxic vs. normoxic conditions and...

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Bibliographic Details
Main Authors: Alicja Głuszko, Mirosław J. Szczepański, Theresa L. Whiteside, Torsten E. Reichert, Jacek Siewiera, Nils Ludwig
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
small extracellular vesicles
exosomes
hypoxia
proteomics
HNSCC
Online Access:https://www.mdpi.com/2072-6694/13/16/4176

Internet

https://www.mdpi.com/2072-6694/13/16/4176

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