Enhanced protective efficacy of nonpathogenic recombinant leishmania tarentolae expressing cysteine proteinases combined with a sand fly salivary antigen.

Novel vaccination approaches are needed to prevent leishmaniasis. Live attenuated vaccines are the gold standard for protection against intracellular pathogens such as Leishmania and there have been new developments in this field. The nonpathogenic to humans lizard protozoan parasite, Leishmania (L)...

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Bibliographic Details
Main Authors: Farnaz Zahedifard, Elham Gholami, Tahereh Taheri, Yasaman Taslimi, Fatemeh Doustdari, Negar Seyed, Fatemeh Torkashvand, Claudio Meneses, Barbara Papadopoulou, Shaden Kamhawi, Jesus G Valenzuela, Sima Rafati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3967951?pdf=render