Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

Abstract Background BCG is the most widely used vaccine of all time and remains the only licensed vaccine for use against tuberculosis in humans. BCG also protects other species such as cattle against tuberculosis, but due to its incompatibility with current tuberculin testing regimens remains unlic...

Full description

Bibliographic Details
Main Authors: Tom A. Mendum, Aneesh Chandran, Kerstin Williams, H. Martin Vordermeier, Bernardo Villarreal-Ramos, H. Wu, Albel Singh, Alex A. Smith, Rachel E. Butler, Aravind Prasad, Neeraj Bharti, Ruma Banerjee, Sunitha M. Kasibhatla, Apoorva Bhatt, Graham R. Stewart, Johnjoe McFadden
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Genomics
Subjects:
Mycobacterium bovis BCG
Transposon library
Cattle
Mycobacterium tuberculosis
Pyruvate carboxylase
Cyclopropane-fatty-acyl-phospholipid synthase
Online Access:http://link.springer.com/article/10.1186/s12864-019-5791-1

Internet

http://link.springer.com/article/10.1186/s12864-019-5791-1

Similar Items