Recent Developments in the Functionalization of Betulinic Acid and Its Natural Analogues: A Route to New Bioactive Compounds

Recent Developments in the Functionalization of Betulinic Acid and Its Natural Analogues: A Route to New Bioactive Compounds

Betulinic acid (BA) and its natural analogues betulin (BN), betulonic (BoA), and 23-hydroxybetulinic (HBA) acids are lupane-type pentacyclic triterpenoids. They are present in many plants and display important biological activities. This review focuses on the chemical transformations used to functio...

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Bibliographic Details
Main Authors: Joana L. C. Sousa, Carmen S. R. Freire, Armando J. D. Silvestre, Artur M. S. Silva
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
triterpenes
betulinic acid
betulin
betulonic acid
23-hydroxybetulinic acid
synthesis
functionalization
derivatization
Online Access:http://www.mdpi.com/1420-3049/24/2/355

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http://www.mdpi.com/1420-3049/24/2/355

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