Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope

A high-throughput screening protocol for evaluating chimeric, self-sufficient P450 biocatalysts and their mutants against a panel of substrates was developed, leading to the identification of a number of novel biooxidation activities.

Bibliographic Details
Main Authors: Aélig Robin, Valentin Köhler, Alison Jones, Afruja Ali, Paul P. Kelly, Elaine O'Reilly, Nicholas J. Turner, Sabine L. Flitsch
Format: Article
Language:English
Published: Beilstein-Institut 2011-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.7.173