ω3PUFAs improve hepatic steatosis in postnatal overfed rats and HepG2 cells by inhibiting acetyl‐CoA carboxylase

Abstract Postnatal overfeeding can lead to persistent increases in hepatic lipid synthesis and the risk of nonalcoholic fatty liver disease (NAFLD) in adulthood. The ω3 polyunsaturated fatty acids (ω3PUFAs) exhibit beneficial effects on NAFLD. Here, we employed a rat model and an in vitro HepG2 cell...

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Bibliographic Details
Main Authors: Nan Zhou, Susu Du, Yanyan Dai, Fan Yang, Xiaonan Li
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Food Science & Nutrition
Subjects:
ACC
Online Access:https://doi.org/10.1002/fsn3.2482