Crystal structure of (1R,3aR,7aR)-1-{(S)-1-[(2R,5S)-5-(3-hydroxypentan-3-yl)tetrahydrofuran-2-yl]ethyl}-7a-methyl-2,3,3a,4,5,6,7,7a-octahydro-1H-inden-4-one

Crystal structure of (1R,3aR,7aR)-1-{(S)-1-[(2R,5S)-5-(3-hydroxypentan-3-yl)tetrahydrofuran-2-yl]ethyl}-7a-methyl-2,3,3a,4,5,6,7,7a-octahydro-1H-inden-4-one

The title compound, C21H36O3, contains an oxolane ring, and six defined stereocentres and may serve as a useful synthon for the synthesis of calcitriol analogues. The configurations of the chiral C atoms of the side chain were unambiguously established in the refinement. In the crystal, C—H...O and...

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Bibliographic Details
Main Authors: Andrea Martínez, Hugo Santalla, Fátima Garrido, Aliou Hamady Barry, Mohamed Gaye, Yagamare Fall Diop
Format: Article
Language:English
Published: International Union of Crystallography 2017-02-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
crystal structure
calcitriol
vitamin D
hydrogen bonding
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989016020648

Internet

http://scripts.iucr.org/cgi-bin/paper?S2056989016020648

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