Direct Conversion of Human Dermal Fibroblasts into Cardiomyocyte‐Like Cells Using CiCMC Nanogels Coupled with Cardiac Transcription Factors and a Nucleoside Drug

Direct Conversion of Human Dermal Fibroblasts into Cardiomyocyte‐Like Cells Using CiCMC Nanogels Coupled with Cardiac Transcription Factors and a Nucleoside Drug

Abstract Using direct conversion technology, normal adult somatic cells can be routinely switched from their original cell type into specific differentiated cell types by inducing the expression of differentiation‐related transcription factors. In this study, normal human dermal fibroblasts (NHDFs)...

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Bibliographic Details
Main Authors: Hye Jin Kim, Hyun Jyung Oh, Ji Sun Park, Jung Sun Lee, Jae‐Hwan Kim, Keun‐Hong Park
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Advanced Science
Subjects:
5‐azacytidine
carboxymethyl cellulose
cardiogenic‐specific factors
induced cardiomyocytes
nanogels
Online Access:https://doi.org/10.1002/advs.201901818

Internet

https://doi.org/10.1002/advs.201901818

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