High-resolution crystal structures of protein helices reconciled with three-centered hydrogen bonds and multipole electrostatics.

Theoretical and experimental evidence for non-linear hydrogen bonds in protein helices is ubiquitous. In particular, amide three-centered hydrogen bonds are common features of helices in high-resolution crystal structures of proteins. These high-resolution structures (1.0 to 1.5 Å nominal crystallog...

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Bibliographic Details
Main Authors: Daniel J Kuster, Chengyu Liu, Zheng Fang, Jay W Ponder, Garland R Marshall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0123146