Inhibition of Gap Junctions Sensitizes Primary Glioblastoma Cells for Temozolomide

Inhibition of Gap Junctions Sensitizes Primary Glioblastoma Cells for Temozolomide

Gap junctions have recently been shown to interconnect glioblastoma cells to a multicellular syncytial network, thereby allowing intercellular communication over long distances as well as enabling glioblastoma cells to form routes for brain microinvasion. Against this backdrop gap junction-targeted...

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Bibliographic Details
Main Authors: Anna-Laura Potthoff, Dieter Henrik Heiland, Bernd O. Evert, Filipe Rodrigues Almeida, Simon P. Behringer, Andreas Dolf, Ági Güresir, Erdem Güresir, Kevin Joseph, Torsten Pietsch, Patrick Schuss, Ulrich Herrlinger, Mike-Andrew Westhoff, Hartmut Vatter, Andreas Waha, Matthias Schneider
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
glioblastoma
gap junctions
INI-0602
cell death
c-Jun
Online Access:https://www.mdpi.com/2072-6694/11/6/858

Internet

https://www.mdpi.com/2072-6694/11/6/858

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