Effects of the Thyroid Endocrine System on Gonadal Sex Ratios and Sex-Related Gene Expression in the Pufferfish Takifugu rubripes

Effects of the Thyroid Endocrine System on Gonadal Sex Ratios and Sex-Related Gene Expression in the Pufferfish Takifugu rubripes

To examine the effect and mechanism of thyroid hormone on gonadal sex differentiation, Takifugu rubripes larvae were treated with goitrogen (methimazole, MET, 1000 μg/g), and thyroxine (T4, 2nM) from 25 to 80 days after hatching (dah). Gonadal histology and sex ratios of fish were then determined at...

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Bibliographic Details
Main Authors: Zhen Yuan, Xufang Shen, Hongwei Yan, Jieming Jiang, Binwei Liu, Lei Zhang, Yumeng Wu, Ying Liu, Qi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Endocrinology
Subjects:
Takifugu rubripes
methimazole
thyroid hormone
sex differentiation
RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.674954/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.674954/full

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