Foxo3 gene expression and oxidative status in beta-thalassemia minor subjects

Foxo3 gene expression and oxidative status in beta-thalassemia minor subjects

ABSTRACT Background: Oxidative stress may aggravate symptoms of hemolytic anemias such as beta-thalassemia. FoxO3 activation results in resistance to oxidative stress in fibroblasts and neuronal cell cultures. Objective: The purpose of this research was to study FoxO3 gene expression and oxidative...

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Bibliographic Details
Main Authors: Sandra Stella Lazarte, María Eugenia Mónaco, Magdalena María Terán, Ana Cecilia Haro, Miryam Emilse Ledesma Achem, Blanca Alicia Issé
Format: Article
Language:English
Published: Elsevier
Series:Revista Brasileira de Hematologia e Hemoterapia
Subjects:
Beta-thalassemia trait
Oxidative stress
FoxO3
Thiobarbituric acid reactive species
Erythrocyte catalase activity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842017000200115&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842017000200115&lng=en&tlng=en

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