Development of a Cytocompatible Scaffold from Pig Immature Testicular Tissue Allowing Human Sertoli Cell Attachment, Proliferation and Functionality

Development of a Cytocompatible Scaffold from Pig Immature Testicular Tissue Allowing Human Sertoli Cell Attachment, Proliferation and Functionality

Cryopreservation of immature testicular tissue before chemo/radiotherapy is the only option to preserve fertility of cancer-affected prepubertal boys. To avoid reintroduction of malignant cells, development of a transplantable scaffold by decellularization of pig immature testicular tissue (ITT) abl...

Full description

Bibliographic Details
Main Authors: Maxime Vermeulen, Federico Del Vento, Francesca de Michele, Jonathan Poels, Christine Wyns
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
decellularization
decellularized tissue
fertility preservation
immature testicular tissue
testicular organoid
regenerative medicine
scaffold
extracellular matrix
tissue engineering
Online Access:http://www.mdpi.com/1422-0067/19/1/227

Internet

http://www.mdpi.com/1422-0067/19/1/227

Similar Items