Evaluation of Phytosomal Curcumin as an Anti-inflammatory Agent for Chronic Glial Activation in the GFAP-IL6 Mouse Model

Evaluation of Phytosomal Curcumin as an Anti-inflammatory Agent for Chronic Glial Activation in the GFAP-IL6 Mouse Model

Chronic glial activation is characterized by an increased number of activated microglia and astroglia; these secrete free radicals and cytotoxic cytokines, subsequently causing neuronal damage. This study investigated the hypothesis that a soy-lecithin based phytosomal curcumin formulation can decre...

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Bibliographic Details
Main Authors: Faheem Ullah, Huazheng Liang, Garry Niedermayer, Gerald Münch, Erika Gyengesi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Neuroscience
Subjects:
microglia activation
astrocytes
Iba-1
TSPO
GFAP
neuroinflammation
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00170/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00170/full

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