VNN1 promotes atherosclerosis progression in apoE−/− mice fed a high-fat/high-cholesterol diet

VNN1 promotes atherosclerosis progression in apoE−/− mice fed a high-fat/high-cholesterol diet

Accumulated evidence shows that vanin-1 (VNN1) plays a key part in glucose metabolism. We explored the effect of VNN1 on cholesterol metabolism, inflammation, apoptosis in vitro, and progression of atherosclerotic plaques in apoE−/− mice. Oxidized LDL (Ox-LDL) significantly induced VNN1 expression t...

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Bibliographic Details
Main Authors: Yan-Wei Hu, Shao-Guo Wu, Jing-Jing Zhao, Xin Ma, Jing-Bo Lu, Jian-cheng Xiu, Yuan Zhang, Chuan Huang, Yu-Rong Qiu, Yan-Hua Sha, Ji-Juan Gao, Yan-Chao Wang, Shu-Fen Li, Jia-Yi Zhao, Lei Zheng, Qian Wang
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein E
oxidized low density lipoprotein
vanin-1
inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520352123

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http://www.sciencedirect.com/science/article/pii/S0022227520352123

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