Two Separate Tyrosine-Based YXXL/Φ Motifs within the Glycoprotein E Cytoplasmic Tail of Bovine Herpesvirus 1 Contribute in Virus Anterograde Neuronal Transport

Two Separate Tyrosine-Based YXXL/Φ Motifs within the Glycoprotein E Cytoplasmic Tail of Bovine Herpesvirus 1 Contribute in Virus Anterograde Neuronal Transport

Bovine herpesvirus 1 (BHV-1) causes respiratory infection and abortion in cattle. Following a primary infection, BHV-1 establishes lifelong latency in the trigeminal ganglia (TG). Periodic reactivation of the latent virus in TG neurons results in anterograde virus transport to nerve endings in the n...

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Bibliographic Details
Main Authors: Hocine Yezid, Christian T. Lay, Katrin Pannhorst, Shafiqul I. Chowdhury
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
BHV-1
glycoprotein E
anterograde neuronal traffic
gE CT domain
YXXL/Φ sorting motifs
compartmentalized primary neurons
Online Access:https://www.mdpi.com/1999-4915/12/9/1025

Internet

https://www.mdpi.com/1999-4915/12/9/1025

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