A mouse model for studying the clearance of hepatitis B virus in vivo using a luciferase reporter.

Hepatitis B virus(HBV) infection remains a global problem, despite the effectiveness of the Hepatitis B vaccine in preventing infection. The resolution of Hepatitis B virus infection has been believed to be attributable to virus-specific immunity. In vivo direct evaluation of anti-HBV immunity in th...

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Bibliographic Details
Main Authors: Sheng-qiang Liang, Juan Du, Hu Yan, Qian-qian Zhou, Yong Zhou, Zhen-nan Yuan, Shao-duo Yan, Qiu-xia Fu, Xiao-hui Wang, Shuai-zheng Jia, Jian-chun Peng, Yang-gen Zhang, Lin-sheng Zhan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3618179?pdf=render