Re-expression of REG family and DUOXs genes in CRC organoids by co-culturing with CAFs

Re-expression of REG family and DUOXs genes in CRC organoids by co-culturing with CAFs

Abstract Organoids derived from epithelial tumors have recently been utilized as a preclinical model in basic and translational studies. This model is considered to represent the original tumor in terms of 3D structure, genetic and cellular heterogeneity, but not tumor microenvironment. In this stud...

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Bibliographic Details
Main Authors: Mie Naruse, Masako Ochiai, Shigeki Sekine, Hirokazu Taniguchi, Teruhiko Yoshida, Hitoshi Ichikawa, Hiromi Sakamoto, Takashi Kubo, Kenji Matsumoto, Atsushi Ochiai, Toshio Imai
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81475-2

Internet

https://doi.org/10.1038/s41598-021-81475-2

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