Small Residues Inhibit Homo-Dimerization of the Human Carbonic Anhydrase XII Transmembrane Domain

Amino acids with small side chains and motifs of small residues in a distance of four are rather abundant in human single-span transmembrane helices. While interaction of such helices appears to be common, the role of the small residues in mediating and/or stabilizing transmembrane helix oligomers r...

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Bibliographic Details
Main Authors: Florian Cymer, Dirk Schneider
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/11/7/512