DNA methylation profiling across the spectrum of HPV-associated anal squamous neoplasia.

Changes in host tumor genome DNA methylation patterns are among the molecular alterations associated with HPV-related carcinogenesis. However, there is little known about the epigenetic changes associated specifically with the development of anal squamous cell cancer (SCC). We sought to characterize...

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Bibliographic Details
Main Authors: Jonathan M Hernandez, Erin M Siegel, Bridget Riggs, Steven Eschrich, Abul Elahi, Xiaotao Qu, Abidemi Ajidahun, Anders Berglund, Domenico Coppola, William M Grady, Anna R Giuliano, David Shibata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511539?pdf=render