Serum YB-1 (Y-box binding protein 1) as a biomarker of bone disease progression in patients with breast cancer and bone metastases

YB-1 (Y-box binding protein 1) is a multifunctional cold-shock protein that has been implicated in all hallmarks of cancer. Elevated YB-1 protein level was associated with poor prognosis in several types of cancers, including breast cancer (BC), where it is a marker of decreased overall survival (OS...

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Main Authors: A.R. Ferreira, M. Bettencourt, I. Alho, A.L. Costa, A.R. Sousa, A. Mansinho, C. Abreu, C. Pulido, D. Macedo, I. Vendrell, T.R. Pacheco, L. Costa, S. Casimiro
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Journal of Bone Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212137416301245