Antiretroviral treatment start-time during primary SIV(mac) infection in macaques exerts a different impact on early viral replication and dissemination.

Antiretroviral treatment start-time during primary SIV(mac) infection in macaques exerts a different impact on early viral replication and dissemination.

BACKGROUND: The time of infection is rarely known in human cases; thus, the effects of delaying the initiation of antiretroviral therapy (ART) on the peripheral viral load and the establishment of viral reservoirs are poorly understood. METHODOLOGY/PRINCIPAL FINDINGS: Six groups of macaques, infecte...

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Bibliographic Details
Main Authors: Pierre Sellier, Abdelkrim Mannioui, Olivier Bourry, Nathalie Dereuddre-Bosquet, Benoit Delache, Patricia Brochard, Julien Calvo, Sophie Prévot, Pierre Roques
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2868019?pdf=render

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http://europepmc.org/articles/PMC2868019?pdf=render

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