Inactivation of aPKClambda reveals a context dependent allocation of cell lineages in preimplantation mouse embryos.

BACKGROUND:During mammalian preimplantation development, lineage divergence seems to be controlled by the interplay between asymmetric cell division (once cells are polarized) and positional information. In the mouse embryo, two distinct cell populations are first observed at the 16-cell stage and c...

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Bibliographic Details
Main Authors: Nicolas Dard, Tran Le, Bernard Maro, Sophie Louvet-Vallée
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2741596?pdf=render