Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130)

Summary Cullin-RING ubiquitin ligases (CRLs) mediate the ubiquitination of numerous protein substrates and target them for proteasomal degradation. The function of CRLs is under tight regulation by Cullin-binding proteins. It has been reported that the Spliceosome-associated protein 130 (SAP130/SF3b...

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Bibliographic Details
Main Authors: Lucia Cordero-Espinoza, Thilo Hagen
Format: Article
Language:English
Published: The Company of Biologists 2013-06-01
Series:Biology Open
Subjects:
p27
Online Access:http://bio.biologists.org/content/2/8/838