Human Norovirus Histo-Blood Group Antigen (HBGA) Binding Sites Mediate the Virus Specific Interactions with Lettuce Carbohydrates

Human Norovirus Histo-Blood Group Antigen (HBGA) Binding Sites Mediate the Virus Specific Interactions with Lettuce Carbohydrates

Lettuce is often implicated in human norovirus (HuNoV) foodborne outbreaks. We identified H-like histo-blood group antigens (HBGAs) on lettuce leaves as specific binding moieties for virus-like particles (VLPs) of HuNoV GII.4/HS194/2009 strain. The objective of this study was to determine whether Hu...

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Bibliographic Details
Main Authors: Malak A. Esseili, Xiang Gao, Patricia Boley, Yixuan Hou, Linda J. Saif, Paul Brewer-Jensen, Lisa C. Lindesmith, Ralph S. Baric, Robert L. Atmar, Qiuhong Wang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Viruses
Subjects:
Foodborne viruses
Human norovirus
Lettuce
Histo-blood group antigens
Virus-lettuce interactions
Virus-like particles
mutations
H-like antigens
virus HBGA-binding sites
Online Access:https://www.mdpi.com/1999-4915/11/9/833

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https://www.mdpi.com/1999-4915/11/9/833

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