Proteomics of REPLICANT perfusate detects changes in the metastatic lymph node microenvironment

Proteomics of REPLICANT perfusate detects changes in the metastatic lymph node microenvironment

Abstract In breast cancer (BC), detecting low volumes of axillary lymph node (ALN) metastasis pre-operatively is difficult and novel biomarkers are needed. We recently showed that patient-derived ALNs can be sustained ex-vivo using normothermic perfusion. We now compare reactive (tumour-free; n = 5)...

Full description

Bibliographic Details
Main Authors: Julia Stevenson, Rachel Barrow-McGee, Lu Yu, Angela Paul, David Mansfield, Julie Owen, Natalie Woodman, Rachael Natrajan, Syed Haider, Cheryl Gillett, Andrew Tutt, Sarah E. Pinder, Jyoti Choudary, Kalnisha Naidoo
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00227-7

Internet

https://doi.org/10.1038/s41523-021-00227-7

Similar Items