Constructing a gnotobiotic mouse model with a synthetic human gut microbiome to study host–microbe cross talk

Constructing a gnotobiotic mouse model with a synthetic human gut microbiome to study host–microbe cross talk

Summary: Reproducible in vivo models are necessary to address functional aspects of the gut microbiome in various diseases. Here, we present a gnotobiotic mouse model that allows for the investigation of specific microbial functions within the microbiome. We describe how to culture 14 different well...

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Bibliographic Details
Main Authors: Alex Steimle, Alessandro De Sciscio, Mareike Neumann, Erica T. Grant, Gabriel V. Pereira, Hiroshi Ohno, Eric C. Martens, Mahesh S. Desai
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:STAR Protocols
Subjects:
Immunology
Microbiology
Model Organisms
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721003142

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http://www.sciencedirect.com/science/article/pii/S2666166721003142

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