Shedding light on the elusive role of endothelial cells in cytomegalovirus dissemination.

Cytomegalovirus (CMV) is frequently transmitted by solid organ transplantation and is associated with graft failure. By forming the boundary between circulation and organ parenchyma, endothelial cells (EC) are suited for bidirectional virus spread from and to the transplant. We applied Cre/loxP-medi...

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Bibliographic Details
Main Authors: Torsten Sacher, Joachim Andrassy, Aivars Kalnins, Lars Dölken, Stefan Jordan, Jürgen Podlech, Zsolt Ruzsics, Karl-Walter Jauch, Matthias J Reddehase, Ulrich H Koszinowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3219709?pdf=render