RPamide neuropeptides NLP-22 and NLP-2 act through GnRH-like receptors to promote sleep and wakefulness in C. elegans

RPamide neuropeptides NLP-22 and NLP-2 act through GnRH-like receptors to promote sleep and wakefulness in C. elegans

Abstract Sleep and wakefulness are fundamental behavioral states of which the underlying molecular principles are becoming slowly elucidated. Transitions between these states require the coordination of multiple neurochemical and modulatory systems. In Caenorhabditis elegans sleep occurs during a la...

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Bibliographic Details
Main Authors: Petrus Van der Auwera, Lotte Frooninckx, Kristen Buscemi, Ryan T. Vance, Jan Watteyne, Olivier Mirabeau, Liesbet Temmerman, Wouter De Haes, Luca Fancsalszky, Alexander Gottschalk, David M. Raizen, Matthew D. Nelson, Liliane Schoofs, Isabel Beets
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-66536-2

Internet

https://doi.org/10.1038/s41598-020-66536-2

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