BRAFV600E mutation analysis in patients with metastatic colorectal cancer (mCRC) in daily clinical practice: correlations with clinical characteristics, and its impact on patients' outcome.

BRAFV600E mutation analysis in patients with metastatic colorectal cancer (mCRC) in daily clinical practice: correlations with clinical characteristics, and its impact on patients' outcome.

To prospectively evaluate the usefulness of the BRAFV600E mutation detection in daily clinical practice in patients with metastatic Colorectal Cancer (mCRC).504 mCRC patients treated with systemic chemotherapy ± biologics were analyzed.A statistically significant higher incidence of the BRAF mutatio...

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Bibliographic Details
Main Authors: Zacharenia Saridaki, Maria Tzardi, Maria Sfakianaki, Chara Papadaki, Alexandra Voutsina, Aristea Kalykaki, Ippokratis Messaritakis, Kyriakos Mpananis, Dimitris Mavroudis, Efstathios Stathopoulos, Vassilis Georgoulias, John Souglakos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3867547?pdf=render

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http://europepmc.org/articles/PMC3867547?pdf=render

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