Molecular changes in the early phase of renin-dependent cardiac hypertrophy in hypertensive cyp1a1 transgenic rats

An early response to high arterial pressure is the development of cardiac hypertrophy. Functional and transcriptional regulation of ion channels and Ca 2+ handling proteins are involved in this process but the relative contribution of each is unclear. In this study, we investigated the expression of...

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Bibliographic Details
Main Authors: Christiane Kunert-Keil, Martin Landsberger, Franziska Jantzen, Felix Niessner, Heyo K Kroemer, Stephan B Felix, Heinrich Brinkmeier, Jörg Peters
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2013-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320312460070