Liquid chromatography--tandem mass spectrometry method for simultaneous determination of albendazole and albendazole sulfoxide in human plasma for bioequivalence studies

Liquid chromatography--tandem mass spectrometry method for simultaneous determination of albendazole and albendazole sulfoxide in human plasma for bioequivalence studies

An improved high performance liquid chromatography--tandem mass spectrometry (LC–MS/MS) method has been developed for sensitive and rapid determination of albendazole (ABZ) and its active metabolite, albendazole sulfoxide (ABZSO), in the positive ionization mode. The method utilized solid phase extr...

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Bibliographic Details
Main Authors: Dhiraj M. Rathod, Keyur R. Patel, Hiren N. Mistri, Arvind G. Jangid, Pranav S. Shrivastav, Mallika Sanyal
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Albendazole
Albendazole sulfoxide
LC > MS/MS
Solid phase extraction
Bioequivalence study
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177916300065

Internet

http://www.sciencedirect.com/science/article/pii/S2095177916300065

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