Construction and Validation of Subject-Specific Biventricular Finite-Element Models of Healthy and Failing Swine Hearts From High-Resolution DT-MRI

Construction and Validation of Subject-Specific Biventricular Finite-Element Models of Healthy and Failing Swine Hearts From High-Resolution DT-MRI

Predictive computational modeling has revolutionized classical engineering disciplines and is in the process of transforming cardiovascular research. This is particularly relevant for investigating emergent therapies for heart failure, which remains a leading cause of death globally. The creation of...

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Bibliographic Details
Main Authors: Kevin L. Sack, Eric Aliotta, Daniel B. Ennis, Jenny S. Choy, Ghassan S. Kassab, Julius M. Guccione, Thomas Franz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Physiology
Subjects:
heart failure
subject-specific
finite element method
realistic simulation
ventricular function
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00539/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.00539/full

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