Rationalization of allosteric pathway in Thermus sp. GH5 methylglyoxal synthase
A sequence of 10 amino acids at the C-terminus region ofmethylglyoxal synthase from Escherichia coli (EMGS) providesan arginine, which plays a crucial role in forming a salt bridgewith a proximal aspartate residue in the neighboring subunit,consequently transferring the allosteric signal between sub...
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Format: | Article |
Language: | English |
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Korean Society for Biochemistry and Molecular Biology
2012-12-01
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Series: | BMB Reports |
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Online Access: | http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTE0MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS0xMiU1RDEyMTIyNjE2NDZfJTI4NzQ4LTc1MyUyOUJNQl8xMS0xMzgucGRm |