Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals.

Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals.

The SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo. We performed this study to validate the model with representatives of all four classes of licensed antiretrovirals.Endpoint analyses for quantification of Thy/Liv imp...

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Bibliographic Details
Main Authors: Cheryl A Stoddart, Cheryl A Bales, Jennifer C Bare, George Chkhenkeli, Sofiya A Galkina, April N Kinkade, Mary E Moreno, José M Rivera, Rollie E Ronquillo, Barbara Sloan, Paul L Black
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1925140?pdf=render

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http://europepmc.org/articles/PMC1925140?pdf=render

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