Group 3 Innate Lymphoid Cells Protect Steatohepatitis From High-Fat Diet Induced Toxicity

Group 3 Innate Lymphoid Cells Protect Steatohepatitis From High-Fat Diet Induced Toxicity

Background and Aims: Emerging evidence has revealed that innate lymphoid cells (ILCs) play a key role in regulating metabolic disorders. Here, we investigated the role of group 3 ILCs (ILC3s) in the modulation of Non-alcoholic fatty liver disease (NAFLD).Methods: RORγ gfp/gfp (RORgt KI/KI) and Rag2−...

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Bibliographic Details
Main Authors: Masahide Hamaguchi, Takuro Okamura, Takuya Fukuda, Kensuke Nishida, Yuta Yoshimura, Yoshitaka Hashimoto, Emi Ushigome, Naoko Nakanishi, Saori Majima, Mai Asano, Masahiro Yamazaki, Hiroshi Takakuwa, Masakazu Kita, Michiaki Fukui
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
ILC
IL-22
IL-23
NASH
NAFLD
steatosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.648754/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.648754/full

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