Enzymatic sialylation of IgA1 O-glycans: implications for studies of IgA nephropathy.

Enzymatic sialylation of IgA1 O-glycans: implications for studies of IgA nephropathy.

Patients with IgA nephropathy (IgAN) have elevated circulating levels of IgA1 with some O-glycans consisting of galactose (Gal)-deficient N-acetylgalactosamine (GalNAc) with or without N-acetylneuraminic acid (NeuAc). We have analyzed O-glycosylation heterogeneity of naturally asialo-IgA1 (Ale) myel...

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Bibliographic Details
Main Authors: Kazuo Takahashi, Milan Raska, Milada Stuchlova Horynova, Stacy D Hall, Knud Poulsen, Mogens Kilian, Yoshiyuki Hiki, Yukio Yuzawa, Zina Moldoveanu, Bruce A Julian, Matthew B Renfrow, Jan Novak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4053367?pdf=render

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http://europepmc.org/articles/PMC4053367?pdf=render

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