N,N-Dimethyl-D-erythro-Sphingosine Inhibits Store-Operated Ca2+ Entry in U937 Monocytes

N,N-Dimethyl-D-erythro-Sphingosine Inhibits Store-Operated Ca2+ Entry in U937 Monocytes

Calcium is a ubiquitous second messenger that controls a broad range of cellular functions, and store-operated calcium entry (SOCE) is the primary mechanism of regulated Ca2+ entry in non-excitable immunocytes. In this study, we found that N,N-dimethyl-D-erythro-sphingosine (DMS) inhibited SOCE. In...

Full description

Bibliographic Details
Main Authors: Ji-Yeong Jo, Hyo-Lim Kim, Yun-Kyung Lee, Hideaki Tomura, Yoe-Sik Bae, Fumikazu Okajima, Dong-Soon Im
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319314173

Internet

http://www.sciencedirect.com/science/article/pii/S1347861319314173

Similar Items