Weekly doxorubicin increases coronary arteriolar wall and adventitial thickness.

Doxorubicin (DOX) is associated with premature cardiovascular events including myocardial infarction. This study was performed to determine if the weekly administration of DOX influenced coronary arteriolar medial and/or adventitial wall thickening.Thirty-two male Sprague-Dawley rats aged 25.1± 2.4...

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Bibliographic Details
Main Authors: Delrae M Eckman, R Brandon Stacey, Robert Rowe, Ralph D'Agostino, Nancy D Kock, David C Sane, Frank M Torti, Joseph Yeboah, Susan Workman, Kimberly S Lane, W Gregory Hundley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3578811?pdf=render