Development of transgenic minipigs with expression of antimorphic human cryptochrome 1.

Minipigs have become important biomedical models for human ailments due to similarities in organ anatomy, physiology, and circadian rhythms relative to humans. The homeostasis of circadian rhythms in both central and peripheral tissues is pivotal for numerous biological processes. Hence, biological...

Full description

Bibliographic Details
Main Authors: Huan Liu, Yong Li, Qiang Wei, Chunxin Liu, Lars Bolund, Gábor Vajta, Hongwei Dou, Wenxian Yang, Ying Xu, Jing Luan, Jun Wang, Huanming Yang, Nicklas Heine Staunstrup, Yutao Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24146819/?tool=EBI