Wedelolactone alleviates doxorubicin-induced inflammation and oxidative stress damage of podocytes by IκK/IκB/NF-κB pathway

Wedelolactone alleviates doxorubicin-induced inflammation and oxidative stress damage of podocytes by IκK/IκB/NF-κB pathway

The acute kidney injury(AKI) caused by nephrotoxic drugs contributes to inflammation and oxidative injury in podocytes. Wedelolactone (WED), a natural compound, is found with activities as anti-inflammation, anti-oxidative, anti-free radical,and etc. In this present study, MPC-5 cells were exposed t...

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Bibliographic Details
Main Authors: Mao-mao Zhu, Long Wang, Dang Yang, Chao Li, Shi-ting Pang, Xing-hua Li, Ru Li, Bing Yang, Yuan-pei Lian, Liang Ma, Qing-lin Lv, Xiao-bin Jia, Liang Feng
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Wedelolactone
Doxorubicin
Podocyte
Inflammation
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219316713

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http://www.sciencedirect.com/science/article/pii/S0753332219316713

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