Characterization of inhibitory GABA-A receptor activation during spreading depolarization in brain slice.

Spreading depolarization (SD) is a slowly propagating wave of near complete depolarizations of neurons and glia. Previous studies have reported large GABA releases during SD, but there is limited understanding of how GABA release and receptor activation are regulated and influence the propagating SD...

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Bibliographic Details
Main Authors: Isamu Aiba, C William Shuttleworth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4206427?pdf=render